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m8 Pharmaceuticals and Vectans Pharma signed an exclusive licensing agreement of Loramyc® (miconazole Lauriad®) for Mexico and Brazil.

February 4th, 2020

 

m8 Pharmaceuticals and Vectans Pharma, announced they have signed an exclusive licensing agreement whereby m8 will have the rights to register and commercialize Loramyc® (miconazole) for Mexico and Brazil. Loramyc® is an antifungal agent, administered as a muco-adhesive buccal tablet for the treatment of oropharyngeal candidiasis in immunocompromised patients. Vectans received its first Loramyc® marketing authorization in France in October 2006. Loramyc® has since been registered in 26 European countries, in South Korea, Japan and in the United States amongst others.

 

Loramyc® is approved for the treatment of Oropharyngeal Candidiasis in immunocompromised patients, particularly those with head and neck cancers who have undergone radiotherapy, and those infected by HIV. Loramyc® is an innovative drug specifically developed for Oropharyngeal Candidiasis in immunodepressed patients, who frequently suffer an associated mucositis. Loramyc® offers an optimized anti-fungal treatment with the same order of efficacy as systemic therapies, with the advantage that it specifically targets the mouth and the oropharynx.

 

The new therapeutic approach uses an innovative delivery system based on a mucoadhesive buccal tablet (Lauriad®technology). This ensures an early and extended release of the active component at the site of the infection, with only one dose per day. The targeted approach reduces the risk of drug interactions and systemic effects, key issues for patients undergoing a multiplicity of treatments. The therapy is also designed to solve epidemiological and ecological problems caused by the emergence of resistant fungal infections.

 

m8 Pharmaceuticals continues its commitment to bringing innovative products to the Latin American region and this agreement reinforces its strategic focus in the area of oncology, further contributing to the supportive care of these patients in the region.

 

 “We are very excited to be collaborating with Vectans Pharma on this innovative product. Oravig®/ Loramyc® has the potential to become the first targeted treatment in tablet form for oropharyngeal candidiasis in Mexico and Brazil, to provide an important addition to available treatments, and to maximize patients’ compliance and improve their quality of life.” said Joel Barlan, m8’s CEO. Commenting on the agreement Jerome Theron, CEO of Vectans mentioned “This partnership is very relevant for us given Moksha8's expertise and leadership position in Mexico and Brazil. It is an important step in our development plan that reinforces our international strategy”.  Jérôme Théron, co-founder and CEO”

 

About Oropharyngeal Candidiasis

 

Fungal infections of the oral mucosa are most frequently caused by Candida species, with C. albicans being the most common species associated with such infections. Oropharyngeal candidiasis is commonly found in immunocompromised patients, including HIV and cancer patients, and in other chronic disease states such as diabetes. For instance, oropharyngeal candidiasis is the most frequently occurring infection in head and neck cancer patients undergoing radiation therapy. The clinical presentation of oropharyngeal candidiasis is variable with symptoms including soreness, burning, and/or altered taste. The signs of clinical candidiasis usually include white pseudomembraneous plaques and patches (thrush), erythematous lesions or occasionally angular cheilitis. Left untreated, the condition may progress to involve the esophagus or to more serious systemic complications.

 

About Vectans pharma

 

Vectans Pharma is an international pharmaceutical company offering new therapeutic perspectives to the pharmaceutical industry thanks to an innovative drug delivery system (Lauriad Technology). Our drugs – Sitavig (acyclovir lauriad) and Loramyc/Oravig/Oravi (miconazole lauriad) - have been developed based on this technology which offers a new route of administration aiming to improve the benefit of patients and are already commercialized through license agreements in the US, Europe and Japan.

 

About m8

 

m8 is a specialty pharmaceutical company focused on licensing, marketing and distributing innovative and established therapeutics in the two largest Latin America markets: Brazil and Mexico. m8 is a Montreux Equity Partners portfolio company.

 

About Montreux

 

Montreux Equity Partners is a private investment firm focused on making growth capital investments in the leading companies of tomorrow. Its portfolio companies address the most compelling trends in global health. The firm is currently investing out of its sixth fund.

 

For more information please contact:

 

Joel Barlan

Chief Executive Officer

T: +52 (55) 4431 2933

us.wm@moksha8.com

 

Rafael Ferrer

Vice President of Corporate Development

T: +1 (305) 299 6998

rafael.ferrer@moksha8.com

Jérôme Théron

Co-founder & Chief Executive Officer

T: +33 1 46 02 02 28

jerome.theron@vectans.com

 

COPYRIGHT © 2006-2020 MOKSHA8 PHARMACEUTICALS, INC. ALL RIGHTS RESERVED. THIS INFORMATION—INCLUDING PRODUCT INFORMATION—IS INTENDED ONLY FOR RESIDENTS OF THE UNITED STATES. THE PRODUCTS DISCUSSED HEREIN MAY HAVE DIFFERENT LABELING IN DIFFERENT COUNTRIES.

 

PRIVACY POLICY | LEGAL DISCLAIMER | LINKEDIN | ENGLISH | PORTUGUESE | SPANISH

moksha8 Mexico will commercialize Duaklir and Eklira, the Astra Zeneca treatments indicated for Chronic Obstructive Pulmonary Disease

December 11th 2018

 

moksha8 Mexico and Astra Zeneca, a leading pharmaceutical company in respiratory therapies, have signed an agreement under which moksha8 Mexico will assume responsibility for promoting and distributing Duaklir and Eklira (aclidinium bromide/formoterol fumarate dihydrate 400/12 μg) in the Mexican territory. Duaklir and Eklira are indicated for the treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

 

COPD is a progressive disease associated mainly with tobacco smoking, air pollution or occupational exposure, which can cause obstruction of airflow in the lungs resulting in debilitating bouts of breathlessness. It affects an estimated 300 million people worldwide and is predicted to be the third leading cause of death by 2030*.

 

The PLATINO study described the epidemiology of COPD in five major Latin American cities. This population-based study reported crude prevalence rates of COPD of 7.8% in Mexico City**.

 

Approximately 90 per cent of COPD patients experience symptoms such as breathlessness and coughing during at least one part of the day and Eklira /Duaklir provides patients with a safe, effective way to improve breathlessness and lung function to these patients.

 

Joel Barlan, moksha8 CEO said: “This strategic partnership will strengthen our pharmaceutical business, accelerating the build of our pipeline and our presence in the respiratory area. Also, we are pleased to continue providing such excellent products for all COPD patients in Mexico.”

 

This agreement represents an immediate opportunity for moksha 8 to build its respiratory portfolio and presence, and these products will add new revenue growth.

*World Health Organization. Burden of COPD.

**Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): a prevalence study. Lancet 2005; 366: 1875–1881

 

 

Montreux Partners Portfolio Company Moksha8 Announces The Appointment Of Mariano Garcia-Valiño To Its Board Of Directors

Berwin, Pennsylvania, USA, December 10th 2018

 

moksha8, a specialty pharmaceutical company, announces the appointment of Mariano Garcia-Valiño as a Board Member and Chairman of its Compensation and Business Development Committees.

 

Mariano has been active at the intersection of healthcare, deal-making and entrepreneurship for over 25 years, experiencing the space from many different angles, be it by building and operating companies, leading M&A and licensing transactions, working for some of the premier players in the business or managing investments for professional equity firms.

 

Recently, Mariano stepped down as CEO of Biotoscana Investments (BR:GBIO33), a company he architected, launched and took public in a transaction that was the largest healthcare IPO in the Americas in 2017 and the region’s first cross-border IPO in a decade.   Under his leadership, the company acquired, merged and transformed several local pharmaceutical players into a streamlined 10-country leading specialty player and closed licensing deals for over 40 novel compounds with some of the premier players in the world.

 

“We are very excited to have Mariano join our Board”, said Daniel K. Turner III, Founding Partner of Montreux.  “He brings invaluable experience in building Latin-American platforms and a unique track record in licensing and M&A. We believe he will be instrumental in taking Moksha8 to the next level”.

 

“I am very excited to work with the team at Montreux and Moksha8, whom I have known for several years and with whom we share a passion for building great businesses”, said Mr. Garcia-Valiño.   “Mariano is joining at a pivotal time”, added Joel Barlan, CEO of Moksha8.  “The company is leaving its start-up phase and prepared for accelerated development.   We believe Moksha8 will benefit highly from his experience”.

 

Mr. Garcia-Valiño holds an Engineering degree from Universidad de Buenos Aires and an MBA from the Harvard Business School.  He is based in Montevideo, Uruguay.

 

moksha8 Pharmaceuticals and CheplaPharm completed a strategic partnership to distribute Questran in Mexico and Brazil

October 31st, 2018

 

moksha8 Pharmaceuticals and the Germany Laboratory, CHEPLAPHARM Arzneimittel GmbH, have signed an agreement in which moksha8 will commercialize and promote Questran in Mexico and Brazil.

 

Questran (Cholestyramine) is indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low-density lipoprotein [LDL] cholesterol).

 

High level of cholesterol increases the risks of heart disease and stroke. Globally, a third of ischaemic heart disease is attributable to high cholesterol.  Overall, hypercholesterolemia is estimated to cause 2.6 million deaths. Prevalence High cholesterol among adults is 39% worldwide (37% for males and 40% for females) the highest prevalence according to WHO is Europe (54% for both sexes), followed by the Americas (48% for both sexes).

 

In Latin America, lipid abnormalities have a high prevalence and this is related to multiple causes: genetic load and epigenetic modifications combined with a sedentary lifestyle and an inadequate nutrition*.

 

Questran (Cholestyramine) has proven if is used along with a proper diet to lower cholesterol in the blood. Lowering cholesterol helps decrease the risk for strokes and heart attacks.

 

moksha8 and CheplaPharm have an established great partnership since last year with the distribution agreement for Dilatrend in Mexico and, due to the positive results achieved, the companies decided to expand their commercial relationship in the South American country.

 

With this agreement, moksha8 Pharmaceuticals continues with its global diversification strategy and is increasing its cardiology portfolio. In Mexico, Questran is the second product in the cardiology line and in the case of Brazil, Questran will be the therapy with which the subsidiary will enter into the therapeutic area.

 

moksha8 is committed to work hard to maximize the product value of Questran and further contribute to hypercholesterolemia treatments in the LA region.

 

 

* World Health Organization/cholesterol, 2011

 

 

moksha8 Brazil announces a strategic alliance with HRA Pharma to commercialize Lysodren as the first step to build an Oncology line in this Market

March 26th, 2018

 

moksha8 Brazil has entered into a Promotion and Distribution Agreement with HRA Pharma to commercialize Lysodren in Brazil as the first step to build an Oncology line in this country. Lysodren (mitotane tablets) is an oral chemotherapeutic agent indicated for the treatment of inoperable, functional or nonfunctional, adrenal cortical carcinoma and until now the only product available in the market for this type of cancer.

 

Adrenocortical carcinoma (ACC) is a rare and aggressive tumor which peaks in incidence during the first and fifth decades of life. ACC has an estimated worldwide annual incidence of 2 cases per million overall. The highest reported annual incidence of pediatric ACC in the world occurs in Southern Brazil (3.4 per million) and is 10-15-fold higher compared to the United States (U.S.), where the annual incidence of pediatric ACC is 0.2-0.3 cases per million*.

 

With this alliance and the new addition to its portfolio, moksha8 expects higher revenue growth and this expansion into the Oncology therapeutic area allows it to achieve a greater presence in the markets in which it operates.

 

The deal is also relevant for moksha8 because with it, the company continues its philosophy to bring innovative treatments to improving the health and quality of life to patients around the world, especially with rare and aggressive disease as adrenal cortical carcinoma.

 

HRA Pharm, a fast growing, innovative healthcare company with headquarters in Paris, France, affirmed that this partnership allows them to expand the international reach of its Endocrinology and Rare Disease Division in different markets such as Europe, United States, Canada, Brazil and South Korea and strengthens its position as a key player in Adrenal Cortical Carcinoma.

 

The companies expect strong results and a possible expansion of the relationship in the South America Country.

 

 

*Adrenocortical Carcinoma in Adults and Children: A Population-Based Outcomes Study involving 1,623 Patients from the Surveillance, Epidemiology, and End Result (SEER) Database (1973-2012)

Remedy Publications LLC   Published 06 May, 2016

 

 

moksha8 Pharmaceuticals and Daewoong Pharmaceuticals sign exclusive licensing agreement to commercialize Nabota (botulinum toxin) in Brazil

January 29, 2018

 

moksha8 Pharmaceuticals, announced today that it has entered into an exclusive licensing agreement with Daewoong Pharmaceuticals to commercialize botulinum toxin product Nabota in Brazil, the largest economy in Latin America.

 

“We are honored to be partnering with Daewoong Pharmaceuticals, one of the leading research- based companies in the world, in order to help expand the usage of Nabota in Latin America", said Joel Barlan.

 

Under the new agreement, moksha8 will be responsible for marketing authorizations, market access, commercialization, distribution throughout Brazil.

 

moksha8 Brazil will adopt a two-track marketing strategy for Nabota, the company will be in charge of Nabota applied to medical conditions while cosmetic use will be taken care of by GC Aesthetic Brazil, the leading pure play female Aesthetic company.

moksha8 Mexico will commercialize Duaklir and Eklira, the Astra Zeneca treatments indicated for Chronic Obstructive Pulmonary Disease

December 11th 2018

 

moksha8 Mexico and Astra Zeneca, a leading pharmaceutical company in respiratory therapies, have signed an agreement under which moksha8 Mexico will assume responsibility for promoting and distributing Duaklir and Eklira (aclidinium bromide/formoterol fumarate dihydrate 400/12 μg) in the Mexican territory. Duaklir and Eklira are indicated for the treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

 

COPD is a progressive disease associated mainly with tobacco smoking, air pollution or occupational exposure, which can cause obstruction of airflow in the lungs resulting in debilitating bouts of breathlessness. It affects an estimated 300 million people worldwide and is predicted to be the third leading cause of death by 2030*.

 

The PLATINO study described the epidemiology of COPD in five major Latin American cities. This population-based study reported crude prevalence rates of COPD of 7.8% in Mexico City**.

 

Approximately 90 per cent of COPD patients experience symptoms such as breathlessness and coughing during at least one part of the day and Eklira /Duaklir provides patients with a safe, effective way to improve breathlessness and lung function to these patients.

 

Joel Barlan, moksha8 CEO said: “This strategic partnership will strengthen our pharmaceutical business, accelerating the build of our pipeline and our presence in the respiratory area. Also, we are pleased to continue providing such excellent products for all COPD patients in Mexico.”

 

This agreement represents an immediate opportunity for moksha 8 to build its respiratory portfolio and presence, and these products will add new revenue growth.

*World Health Organization. Burden of COPD.

**Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): a prevalence study. Lancet 2005; 366: 1875–1881

 

 

Montreux Partners Portfolio Company Moksha8 Announces The Appointment Of Mariano Garcia-Valiño To Its Board Of Directors

Berwin, Pennsylvania, USA, December 10th 2018

 

moksha8, a specialty pharmaceutical company, announces the appointment of Mariano Garcia-Valiño as a Board Member and Chairman of its Compensation and Business Development Committees.

 

Mariano has been active at the intersection of healthcare, deal-making and entrepreneurship for over 25 years, experiencing the space from many different angles, be it by building and operating companies, leading M&A and licensing transactions, working for some of the premier players in the business or managing investments for professional equity firms.

 

Recently, Mariano stepped down as CEO of Biotoscana Investments (BR:GBIO33), a company he architected, launched and took public in a transaction that was the largest healthcare IPO in the Americas in 2017 and the region’s first cross-border IPO in a decade.   Under his leadership, the company acquired, merged and transformed several local pharmaceutical players into a streamlined 10-country leading specialty player and closed licensing deals for over 40 novel compounds with some of the premier players in the world.

 

“We are very excited to have Mariano join our Board”, said Daniel K. Turner III, Founding Partner of Montreux.  “He brings invaluable experience in building Latin-American platforms and a unique track record in licensing and M&A. We believe he will be instrumental in taking Moksha8 to the next level”.

 

“I am very excited to work with the team at Montreux and Moksha8, whom I have known for several years and with whom we share a passion for building great businesses”, said Mr. Garcia-Valiño.   “Mariano is joining at a pivotal time”, added Joel Barlan, CEO of Moksha8.  “The company is leaving its start-up phase and prepared for accelerated development.   We believe Moksha8 will benefit highly from his experience”.

 

Mr. Garcia-Valiño holds an Engineering degree from Universidad de Buenos Aires and an MBA from the Harvard Business School.  He is based in Montevideo, Uruguay.

 

moksha8 Pharmaceuticals and CheplaPharm completed a strategic partnership to distribute Questran in Mexico and Brazil

October 31st, 2018

 

moksha8 Pharmaceuticals and the Germany Laboratory, CHEPLAPHARM Arzneimittel GmbH, have signed an agreement in which moksha8 will commercialize and promote Questran in Mexico and Brazil.

 

Questran (Cholestyramine) is indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low-density lipoprotein [LDL] cholesterol).

 

High level of cholesterol increases the risks of heart disease and stroke. Globally, a third of ischaemic heart disease is attributable to high cholesterol.  Overall, hypercholesterolemia is estimated to cause 2.6 million deaths. Prevalence High cholesterol among adults is 39% worldwide (37% for males and 40% for females) the highest prevalence according to WHO is Europe (54% for both sexes), followed by the Americas (48% for both sexes).

 

In Latin America, lipid abnormalities have a high prevalence and this is related to multiple causes: genetic load and epigenetic modifications combined with a sedentary lifestyle and an inadequate nutrition*.

 

Questran (Cholestyramine) has proven if is used along with a proper diet to lower cholesterol in the blood. Lowering cholesterol helps decrease the risk for strokes and heart attacks.

 

moksha8 and CheplaPharm have an established great partnership since last year with the distribution agreement for Dilatrend in Mexico and, due to the positive results achieved, the companies decided to expand their commercial relationship in the South American country.

 

With this agreement, moksha8 Pharmaceuticals continues with its global diversification strategy and is increasing its cardiology portfolio. In Mexico, Questran is the second product in the cardiology line and in the case of Brazil, Questran will be the therapy with which the subsidiary will enter into the therapeutic area.

 

moksha8 is committed to work hard to maximize the product value of Questran and further contribute to hypercholesterolemia treatments in the LA region.

 

 

* World Health Organization/cholesterol, 2011

 

 

moksha8 Brazil announces a strategic alliance with HRA Pharma to commercialize Lysodren as the first step to build an Oncology line in this Market

March 26th, 2018

 

moksha8 Brazil has entered into a Promotion and Distribution Agreement with HRA Pharma to commercialize Lysodren in Brazil as the first step to build an Oncology line in this country. Lysodren (mitotane tablets) is an oral chemotherapeutic agent indicated for the treatment of inoperable, functional or nonfunctional, adrenal cortical carcinoma and until now the only product available in the market for this type of cancer.

 

Adrenocortical carcinoma (ACC) is a rare and aggressive tumor which peaks in incidence during the first and fifth decades of life. ACC has an estimated worldwide annual incidence of 2 cases per million overall. The highest reported annual incidence of pediatric ACC in the world occurs in Southern Brazil (3.4 per million) and is 10-15-fold higher compared to the United States (U.S.), where the annual incidence of pediatric ACC is 0.2-0.3 cases per million*.

 

With this alliance and the new addition to its portfolio, moksha8 expects higher revenue growth and this expansion into the Oncology therapeutic area allows it to achieve a greater presence in the markets in which it operates.

 

The deal is also relevant for moksha8 because with it, the company continues its philosophy to bring innovative treatments to improving the health and quality of life to patients around the world, especially with rare and aggressive disease as adrenal cortical carcinoma.

 

HRA Pharm, a fast growing, innovative healthcare company with headquarters in Paris, France, affirmed that this partnership allows them to expand the international reach of its Endocrinology and Rare Disease Division in different markets such as Europe, United States, Canada, Brazil and South Korea and strengthens its position as a key player in Adrenal Cortical Carcinoma.

 

The companies expect strong results and a possible expansion of the relationship in the South America Country.

 

 

*Adrenocortical Carcinoma in Adults and Children: A Population-Based Outcomes Study involving 1,623 Patients from the Surveillance, Epidemiology, and End Result (SEER) Database (1973-2012)

Remedy Publications LLC   Published 06 May, 2016

 

 

moksha8 Pharmaceuticals and Daewoong Pharmaceuticals sign exclusive licensing agreement to commercialize Nabota (botulinum toxin) in Brazil

January 29, 2018

 

moksha8 Pharmaceuticals, announced today that it has entered into an exclusive licensing agreement with Daewoong Pharmaceuticals to commercialize botulinum toxin product Nabota in Brazil, the largest economy in Latin America.

 

“We are honored to be partnering with Daewoong Pharmaceuticals, one of the leading research- based companies in the world, in order to help expand the usage of Nabota in Latin America", said Joel Barlan.

 

Under the new agreement, moksha8 will be responsible for marketing authorizations, market access, commercialization, distribution throughout Brazil.

 

moksha8 Brazil will adopt a two-track marketing strategy for Nabota, the company will be in charge of Nabota applied to medical conditions while cosmetic use will be taken care of by GC Aesthetic Brazil, the leading pure play female Aesthetic company.

moksha8 Mexico will commercialize Duaklir and Eklira, the Astra Zeneca treatments indicated for Chronic Obstructive Pulmonary Disease

December 11th 2018

 

moksha8 Mexico and Astra Zeneca, a leading pharmaceutical company in respiratory therapies, have signed an agreement under which moksha8 Mexico will assume responsibility for promoting and distributing Duaklir and Eklira (aclidinium bromide/formoterol fumarate dihydrate 400/12 μg) in the Mexican territory. Duaklir and Eklira are indicated for the treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

 

COPD is a progressive disease associated mainly with tobacco smoking, air pollution or occupational exposure, which can cause obstruction of airflow in the lungs resulting in debilitating bouts of breathlessness. It affects an estimated 300 million people worldwide and is predicted to be the third leading cause of death by 2030*.

 

The PLATINO study described the epidemiology of COPD in five major Latin American cities. This population-based study reported crude prevalence rates of COPD of 7.8% in Mexico City**.

 

Approximately 90 per cent of COPD patients experience symptoms such as breathlessness and coughing during at least one part of the day and Eklira /Duaklir provides patients with a safe, effective way to improve breathlessness and lung function to these patients.

 

Joel Barlan, moksha8 CEO said: “This strategic partnership will strengthen our pharmaceutical business, accelerating the build of our pipeline and our presence in the respiratory area. Also, we are pleased to continue providing such excellent products for all COPD patients in Mexico.”

 

This agreement represents an immediate opportunity for moksha 8 to build its respiratory portfolio and presence, and these products will add new revenue growth.

*World Health Organization. Burden of COPD.

**Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): a prevalence study. Lancet 2005; 366: 1875–1881

 

 

Montreux Partners Portfolio Company Moksha8 Announces The Appointment Of Mariano Garcia-Valiño To Its Board Of Directors

Berwin, Pennsylvania, USA, December 10th 2018

 

moksha8, a specialty pharmaceutical company, announces the appointment of Mariano Garcia-Valiño as a Board Member and Chairman of its Compensation and Business Development Committees.

 

Mariano has been active at the intersection of healthcare, deal-making and entrepreneurship for over 25 years, experiencing the space from many different angles, be it by building and operating companies, leading M&A and licensing transactions, working for some of the premier players in the business or managing investments for professional equity firms.

 

Recently, Mariano stepped down as CEO of Biotoscana Investments (BR:GBIO33), a company he architected, launched and took public in a transaction that was the largest healthcare IPO in the Americas in 2017 and the region’s first cross-border IPO in a decade.   Under his leadership, the company acquired, merged and transformed several local pharmaceutical players into a streamlined 10-country leading specialty player and closed licensing deals for over 40 novel compounds with some of the premier players in the world.

 

“We are very excited to have Mariano join our Board”, said Daniel K. Turner III, Founding Partner of Montreux.  “He brings invaluable experience in building Latin-American platforms and a unique track record in licensing and M&A. We believe he will be instrumental in taking Moksha8 to the next level”.

 

“I am very excited to work with the team at Montreux and Moksha8, whom I have known for several years and with whom we share a passion for building great businesses”, said Mr. Garcia-Valiño.   “Mariano is joining at a pivotal time”, added Joel Barlan, CEO of Moksha8.  “The company is leaving its start-up phase and prepared for accelerated development.   We believe Moksha8 will benefit highly from his experience”.

 

Mr. Garcia-Valiño holds an Engineering degree from Universidad de Buenos Aires and an MBA from the Harvard Business School.  He is based in Montevideo, Uruguay.

 

moksha8 Pharmaceuticals and CheplaPharm completed a strategic partnership to distribute Questran in Mexico and Brazil

October 31st, 2018

 

moksha8 Pharmaceuticals and the Germany Laboratory, CHEPLAPHARM Arzneimittel GmbH, have signed an agreement in which moksha8 will commercialize and promote Questran in Mexico and Brazil.

 

Questran (Cholestyramine) is indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low-density lipoprotein [LDL] cholesterol).

 

High level of cholesterol increases the risks of heart disease and stroke. Globally, a third of ischaemic heart disease is attributable to high cholesterol.  Overall, hypercholesterolemia is estimated to cause 2.6 million deaths. Prevalence High cholesterol among adults is 39% worldwide (37% for males and 40% for females) the highest prevalence according to WHO is Europe (54% for both sexes), followed by the Americas (48% for both sexes).

 

In Latin America, lipid abnormalities have a high prevalence and this is related to multiple causes: genetic load and epigenetic modifications combined with a sedentary lifestyle and an inadequate nutrition*.

 

Questran (Cholestyramine) has proven if is used along with a proper diet to lower cholesterol in the blood. Lowering cholesterol helps decrease the risk for strokes and heart attacks.

 

moksha8 and CheplaPharm have an established great partnership since last year with the distribution agreement for Dilatrend in Mexico and, due to the positive results achieved, the companies decided to expand their commercial relationship in the South American country.

 

With this agreement, moksha8 Pharmaceuticals continues with its global diversification strategy and is increasing its cardiology portfolio. In Mexico, Questran is the second product in the cardiology line and in the case of Brazil, Questran will be the therapy with which the subsidiary will enter into the therapeutic area.

 

moksha8 is committed to work hard to maximize the product value of Questran and further contribute to hypercholesterolemia treatments in the LA region.

 

 

* World Health Organization/cholesterol, 2011

 

 

moksha8 Brazil announces a strategic alliance with HRA Pharma to commercialize Lysodren as the first step to build an Oncology line in this Market

March 26th, 2018

 

moksha8 Brazil has entered into a Promotion and Distribution Agreement with HRA Pharma to commercialize Lysodren in Brazil as the first step to build an Oncology line in this country. Lysodren (mitotane tablets) is an oral chemotherapeutic agent indicated for the treatment of inoperable, functional or nonfunctional, adrenal cortical carcinoma and until now the only product available in the market for this type of cancer.

 

Adrenocortical carcinoma (ACC) is a rare and aggressive tumor which peaks in incidence during the first and fifth decades of life. ACC has an estimated worldwide annual incidence of 2 cases per million overall. The highest reported annual incidence of pediatric ACC in the world occurs in Southern Brazil (3.4 per million) and is 10-15-fold higher compared to the United States (U.S.), where the annual incidence of pediatric ACC is 0.2-0.3 cases per million*.

 

With this alliance and the new addition to its portfolio, moksha8 expects higher revenue growth and this expansion into the Oncology therapeutic area allows it to achieve a greater presence in the markets in which it operates.

 

The deal is also relevant for moksha8 because with it, the company continues its philosophy to bring innovative treatments to improving the health and quality of life to patients around the world, especially with rare and aggressive disease as adrenal cortical carcinoma.

 

HRA Pharm, a fast growing, innovative healthcare company with headquarters in Paris, France, affirmed that this partnership allows them to expand the international reach of its Endocrinology and Rare Disease Division in different markets such as Europe, United States, Canada, Brazil and South Korea and strengthens its position as a key player in Adrenal Cortical Carcinoma.

 

The companies expect strong results and a possible expansion of the relationship in the South America Country.

 

 

*Adrenocortical Carcinoma in Adults and Children: A Population-Based Outcomes Study involving 1,623 Patients from the Surveillance, Epidemiology, and End Result (SEER) Database (1973-2012)

Remedy Publications LLC   Published 06 May, 2016

 

 

moksha8 Pharmaceuticals and Daewoong Pharmaceuticals sign exclusive licensing agreement to commercialize Nabota (botulinum toxin) in Brazil

January 29, 2018

 

moksha8 Pharmaceuticals, announced today that it has entered into an exclusive licensing agreement with Daewoong Pharmaceuticals to commercialize botulinum toxin product Nabota in Brazil, the largest economy in Latin America.

 

“We are honored to be partnering with Daewoong Pharmaceuticals, one of the leading research- based companies in the world, in order to help expand the usage of Nabota in Latin America", said Joel Barlan.

 

Under the new agreement, moksha8 will be responsible for marketing authorizations, market access, commercialization, distribution throughout Brazil.

 

moksha8 Brazil will adopt a two-track marketing strategy for Nabota, the company will be in charge of Nabota applied to medical conditions while cosmetic use will be taken care of by GC Aesthetic Brazil, the leading pure play female Aesthetic company.